Helicobacter pylori virulence factors in gastric carcinogenesis
نویسندگان
چکیده
منابع مشابه
Regulation of gastric carcinogenesis by Helicobacter pylori virulence factors.
Helicobacter pylori is the strongest known risk factor for gastric adenocarcinoma, and strains that possess the cag secretion system, which translocates the bacterial effector CagA into host cells, augment cancer risk. H. pylori strains that express the vacuolating cytotoxin or the outer membrane protein OipA are similarly associated with severe pathologic outcomes. We previously reported that ...
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Persistent colonization of the human stomach with Helicobacter pylori is a risk factor for gastric adenocarcinoma, and H. pylori-induced carcinogenesis is dependent on the actions of a bacterial oncoprotein known as CagA. Epidemiological studies have shown that high dietary salt intake is also a risk factor for gastric cancer. To investigate the effects of a high-salt diet, we infected Mongolia...
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ژورنال
عنوان ژورنال: Cancer Letters
سال: 2009
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2008.11.016